Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K ant

Field Value
Model ID13-016-01
Model NameR2CHADS2 Score
Pubmed ID23212720
First AuthorPiccini
JournalCirculation
Year2013
TitleRenal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K ant
Primary Index ConditionArrhythmia
Secondary Index ConditionAtrial Fibrillation
OutcomeStroke
Model Sample Size14264
Cohort Sample Size14264
Number of Events575
Follow-Up DurationLong (>6 months)
AUROC0.587
Calibration Reported1
CovariatesPrior stroke or TIA, Cockcroft/Gault CrCl, <=40 mL/min, Cockcroft/Gault CrCl, 41-50 mL/min, Cockcroft/Gault CrCl, 51-60 mL/min, Cockcroft/Gault CrCl, 61-70 mL/min, Cockcroft/Gault CrCl, 71-80 mL/min, Cockcroft/Gault CrCl, 81-90 mL/min, Cockcroft/Gault CrC
Mesh TermsTo be updated
Number of Validations7

External Validations

Yes
7
0.672
1st Author Year Sample Size AUC Calibration Relatedness
Bautista 2015 98 0.631 No Related
Peguero 2016 2263 0.64 No Mismatch
Abumuaileq 2015 154 0.65 No Related
Piccini 2013 13559 0.672 No Related
Abumuaileq 2015 911 0.7 No Distantly Related
Bautista 2015 524 0.718 No Related
Bautista 2015 426 0.724 No Related