Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation

Field Value
Model ID01-006-01
Model NameCHF, Hypertension, Age, DM, History of Stroke or TIA (CHADS2)
Pubmed ID11401607
First AuthorGage
JournalJournal of the American Medical Association
Year2001
TitleValidation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation
Primary Index ConditionArrhythmia
Secondary Index ConditionAtrial Fibrillation
OutcomeStroke
Model Sample Size1733
Cohort Sample Size1733
Number of Events94
Follow-Up DurationLong (>6 months)
AUROC0.82
Calibration Reported1
CovariatesRecent congestive heart failure; Hypertension; Age at least 75 years; Diabetes mellitus; Prior stroke or transient ischemic attack
Mesh TermsTo be updated
Number of Validations37

External Validations

Yes
37
0.65
1st Author Year Sample Size AUC Calibration Relatedness
Inoue 2006 509 NR No Related
Lu 2017 3036 NR No Mismatch
Siu 2014 9727 0.506 No Related
Lip 2010 1084 0.561 No Distantly Related
Lau 2014 607 0.573 No Mismatch
Piccini 2013 14171 0.575 No Distantly Related
Potpara 2012 345 0.58 No Distantly Related
Bautista 2015 426 0.584 No Related
Barra 2013 555 0.591 No Distantly Related
Guo 2014 441 0.6 No Distantly Related
Bautista 2015 524 0.605 No Related
Saliba 2016 46657 0.606 No Related
Svendsen 2013 1415 0.62 No Mismatch
Bautista 2015 98 0.629 No Related
Olesen 2011 73538 0.633 No Related
Wu 2017 1046 0.638 No Mismatch
Barra 2013 294 0.646 Yes Related
Xing 2016 413 0.647 No Related
Conti 2013 1091 0.648 No Related
Baruch 2007 7329 0.65 No Distantly Related
Welles 2011 916 0.65 No Mismatch
Peguero 2016 2263 0.66 No Mismatch
van Staa 2011 79844 0.66 No Distantly Related
Singer 2013 25306 0.66 No Related
Chua 2014 3183 0.66 No Mismatch
Kinnunen 2015 1314 0.669 No Mismatch
Piccini 2013 13559 0.673 No Related
Rietbrock 2008 51807 0.68 No Related
van den Ham 2015 60594 0.68 No Related
Lin 2011 7920 0.683 No Distantly Related
Singer 2013 10927 0.69 No Related
Huang 2014 747 0.698 No Mismatch
Chan 2014 579 0.7 No Mismatch
Hornero 2012 2910 0.716 Yes Mismatch
Saliba 2016 1053871 0.718 No Mismatch
Wang 2015 141 0.838 No Related
Potpara 2014 240 0.872 No Mismatch