Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation
| Field | Value |
|---|---|
| Model ID | 01-006-01 |
| Model Name | CHF, Hypertension, Age, DM, History of Stroke or TIA (CHADS2) |
| Pubmed ID | 11401607 |
| First Author | Gage |
| Journal | Journal of the American Medical Association |
| Year | 2001 |
| Title | Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation |
| Primary Index Condition | Arrhythmia |
| Secondary Index Condition | Atrial Fibrillation |
| Outcome | Stroke |
| Model Sample Size | 1733 |
| Cohort Sample Size | 1733 |
| Number of Events | 94 |
| Follow-Up Duration | Long (>6 months) |
| AUROC | 0.82 |
| Calibration Reported | 1 |
| Covariates | Recent congestive heart failure; Hypertension; Age at least 75 years; Diabetes mellitus; Prior stroke or transient ischemic attack |
| Mesh Terms | To be updated |
| Number of Validations | 37 |
External Validations
| Yes | |
| 37 | |
| 0.65 |
| 1st Author | Year | Sample Size | AUC | Calibration | Relatedness |
|---|---|---|---|---|---|
| Inoue | 2006 | 509 | NR | No | Related |
| Lu | 2017 | 3036 | NR | No | Mismatch |
| Siu | 2014 | 9727 | 0.506 | No | Related |
| Lip | 2010 | 1084 | 0.561 | No | Distantly Related |
| Lau | 2014 | 607 | 0.573 | No | Mismatch |
| Piccini | 2013 | 14171 | 0.575 | No | Distantly Related |
| Potpara | 2012 | 345 | 0.58 | No | Distantly Related |
| Bautista | 2015 | 426 | 0.584 | No | Related |
| Barra | 2013 | 555 | 0.591 | No | Distantly Related |
| Guo | 2014 | 441 | 0.6 | No | Distantly Related |
| Bautista | 2015 | 524 | 0.605 | No | Related |
| Saliba | 2016 | 46657 | 0.606 | No | Related |
| Svendsen | 2013 | 1415 | 0.62 | No | Mismatch |
| Bautista | 2015 | 98 | 0.629 | No | Related |
| Olesen | 2011 | 73538 | 0.633 | No | Related |
| Wu | 2017 | 1046 | 0.638 | No | Mismatch |
| Barra | 2013 | 294 | 0.646 | Yes | Related |
| 2016 | 413 | 0.647 | No | Related | |
| Conti | 2013 | 1091 | 0.648 | No | Related |
| Baruch | 2007 | 7329 | 0.65 | No | Distantly Related |
| Welles | 2011 | 916 | 0.65 | No | Mismatch |
| Peguero | 2016 | 2263 | 0.66 | No | Mismatch |
| van Staa | 2011 | 79844 | 0.66 | No | Distantly Related |
| Singer | 2013 | 25306 | 0.66 | No | Related |
| Chua | 2014 | 3183 | 0.66 | No | Mismatch |
| Kinnunen | 2015 | 1314 | 0.669 | No | Mismatch |
| Piccini | 2013 | 13559 | 0.673 | No | Related |
| Rietbrock | 2008 | 51807 | 0.68 | No | Related |
| van den Ham | 2015 | 60594 | 0.68 | No | Related |
| Lin | 2011 | 7920 | 0.683 | No | Distantly Related |
| Singer | 2013 | 10927 | 0.69 | No | Related |
| Huang | 2014 | 747 | 0.698 | No | Mismatch |
| Chan | 2014 | 579 | 0.7 | No | Mismatch |
| Hornero | 2012 | 2910 | 0.716 | Yes | Mismatch |
| Saliba | 2016 | 1053871 | 0.718 | No | Mismatch |
| Wang | 2015 | 141 | 0.838 | No | Related |
| Potpara | 2014 | 240 | 0.872 | No | Mismatch |