Predictors of mortality and morbidity in patients with chronic heart failure

Field Value
Model ID06-002-02
Model NameCandesartan in Heart Failure: Assessment of Reduction in Mortality and morbidity (CHARM) - All Cause Mortality
Pubmed ID16219658
First AuthorPocock
JournalEuropean Heart Journal
Year2006
TitlePredictors of mortality and morbidity in patients with chronic heart failure
Primary Index ConditionChronic Heart Failure (CHF)
Secondary Index ConditionN/A
OutcomeMortality
Model Sample Size7599
Cohort Sample Size7599
Number of Events1831
Follow-Up DurationLong (>6 months)
AUROC0.75
Calibration Reported1
CovariatesAge (per 10 years over age 60); Ejection fraction (per 5% decrease below 45); Diabetes: insulin-treated; Diabetes: other; BMI (per 1 kg/m^2 decrease below 27.5); Female; NYHA class III; NYHA class IV; Current smoker; Bundle branch block; Cardiomegaly; Prior HF hospitalization within 6 months; Prior HF hospitalization but not within 6 months; DBP (per 10 mmHg decrease); Diagnosis of CHF over 2 years ago; Previous myocardial infarction; Dependent edema; Heart rate (per 10 bpm); Pulmonary crackles; Pulmonary edema; Mitral regurgitation; Atrial fibrillation; Rest dyspnea; Candesartan (vs. placebo)
Mesh TermsTo be updated
Number of Validations0

External Validations