Model ID | 06-002-02 |
Model Name | Candesartan in Heart Failure: Assessment of Reduction in Mortality and morbidity (CHARM) - All Cause Mortality |
Pubmed ID | 16219658 |
First Author | Pocock |
Journal | European Heart Journal |
Year | 2006 |
Title | Predictors of mortality and morbidity in patients with chronic heart failure |
Primary Index Condition | Chronic Heart Failure (CHF) |
Secondary Index Condition | N/A |
Outcome | Mortality |
Model Sample Size | 7599 |
Cohort Sample Size | 7599 |
Number of Events | 1831 |
Follow-Up Duration | Long (>6 months) |
AUROC | 0.75 |
Calibration Reported | 1 |
Covariates | Age (per 10 years over age 60); Ejection fraction (per 5% decrease below 45); Diabetes: insulin-treated; Diabetes: other; BMI (per 1 kg/m^2 decrease below 27.5); Female; NYHA class III; NYHA class IV; Current smoker; Bundle branch block; Cardiomegaly; Prior HF hospitalization within 6 months; Prior HF hospitalization but not within 6 months; DBP (per 10 mmHg decrease); Diagnosis of CHF over 2 years ago; Previous myocardial infarction; Dependent edema; Heart rate (per 10 bpm); Pulmonary crackles; Pulmonary edema; Mitral regurgitation; Atrial fibrillation; Rest dyspnea; Candesartan (vs. placebo) |
Mesh Terms | To be updated |
Number of Validations | 0 |