Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer

Field Value
Model ID00-005-01
Model NameSimplified Wells Score
Pubmed ID10744147
First AuthorWells
JournalThrombosis and Haemostasis
Year2000
TitleDerivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer
Primary Index ConditionVenous Thromboembolism (VTE)
Secondary Index ConditionDiagnosis
OutcomeVenous Thromboembolism (VTE)
Model Sample Size1008
Cohort Sample Size1008
Number of Events222
Follow-Up DurationModerate (3-6 months)
AUROCNR
Calibration Reported1
CovariatesAn alternative diagnosis is less likely than PE; Heart rate greater than 100; Immobilization or surgery in the previous four weeks; Previous DVT/PE; Hemoptysis; Malignancy (on treatment, treated in the last six months or palliative); Clinical signs and symptoms of DVT (minimum of leg swelling and pain with palpation of the deep veins)
Mesh TermsTo be updated
Number of Validations9

External Validations

Yes
9
0.755
1st Author Year Sample Size AUC Calibration Relatedness
Carrier 2006 535 NR No Related
Runyon 2005 2477 NR Yes Distantly Related
Yap 2007 595 NR No Distantly Related
Kanbay 2007 56 0.42 No Mismatch
Klok 2008 300 0.72 No Distantly Related
Douma 2011 807 0.73 Yes Related
Chagnon 2002 277 0.78 No Related
Posadas-Martinez 2014 613 0.79 Yes Related
Calisir 2009 148 0.823 No Distantly Related