A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey
| Field | Value |
|---|---|
| Model ID | 10-025-01 |
| Model Name | Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly, Drugs/alcohol concomitantly (HAS-BLED) |
| Pubmed ID | 20299623 |
| First Author | Pisters |
| Journal | Chest |
| Year | 2010 |
| Title | A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey |
| Primary Index Condition | Arrhythmia |
| Secondary Index Condition | N/A |
| Outcome | Hemorrhage |
| Model Sample Size | 3978 |
| Cohort Sample Size | 3978 |
| Number of Events | 53 |
| Follow-Up Duration | Long (>6 months) |
| AUROC | 0.72 |
| Calibration Reported | 1 |
| Covariates | Hypertension; Abnormal renal and liver function; Stroke; Bleeding; Labile INRs; Elderly (>65 years); Drugs or alcohol |
| Mesh Terms | To be updated |
| Number of Validations | 24 |
External Validations
| Yes | |
| 24 | |
| 0.63 |
| 1st Author | Year | Sample Size | AUC | Calibration | Relatedness |
|---|---|---|---|---|---|
| Koene | 2014 | 173 | NR | No | Mismatch |
| Wang | 2015 | 141 | 0.502 | No | Distantly Related |
| Kiviniemi | 2014 | 929 | 0.52 | No | Distantly Related |
| Siu | 2014 | 3881 | 0.552 | No | Distantly Related |
| Fauchier | 2016 | 533044 | 0.58 | No | Distantly Related |
| Garcia-Fernandez | 2017 | 1215 | 0.592 | No | Distantly Related |
| Lip | 2012 | 7156 | 0.61 | No | Related |
| Hijazi | 2016 | 14537 | 0.61 | Yes | Related |
| Ye | 2015 | 1142 | 0.61 | No | Mismatch |
| Hijazi | 2016 | 8468 | 0.62 | No | Related |
| Costa | 2015 | 1946 | 0.63 | Yes | Mismatch |
| Riva | 2014 | 681 | 0.63 | No | Mismatch |
| Ye | 2015 | 1163 | 0.63 | No | Mismatch |
| Wallentin | 2014 | 14798 | 0.633 | No | Related |
| Apostolakis | 2012 | 2293 | 0.65 | Yes | Distantly Related |
| Lip | 2011 | 7329 | 0.65 | Yes | Related |
| Smith | 2012 | 157 | 0.67 | No | Mismatch |
| Gorman | 2016 | 105 | 0.68 | No | Distantly Related |
| Barnes | 2014 | 2600 | 0.69 | No | Related |
| Roldan | 2013 | 937 | 0.71 | No | Related |
| Potpara | 2014 | 240 | 0.75 | No | Mismatch |
| Olesen | 2011 | 44771 | 0.795 | No | Related |
| Hsieh | 2015 | 617 | 0.8 | Yes | Mismatch |
| Olesen | 2011 | 73813 | 0.806 | No | Related |