Contemporary model for cardiovascular risk prediction in people with type 2 diabetes

Field Value
Model ID11-060-01
Model NameAction in Diabetes and Vascular disease: preterax and diamicron-MR controlled evaluation (ADVANCE)Risk Engine - Score
Pubmed ID21450612
First AuthorKengne
JournalEuropean Journal of Cardiovascular Prevention and Rehabilitation
Year2011
TitleContemporary model for cardiovascular risk prediction in people with type 2 diabetes
Primary Index ConditionPopulation Sample
Secondary Index ConditionDiabetes Mellitus (DM)
OutcomeMACCE
Model Sample Size7168
Cohort Sample Size7168
Number of Events473
Follow-Up DurationLong (>6 months)
AUROCNR
Calibration Reported1
CovariatesAge at diagnosis: 29-34 years; Age at diagnosis: 35-39 years; Age at diagnosis: 40-44 years; Age at diagnosis: 45-50 years; Age at diagnosis: 51-56 years; Age at diagnosis: 57-62 years; Age at diagnosis: 63-68 years; Age at diagnosis: 69-74 years; Age at diagnosis: 75-80 years; Age at diagnosis: 81-86 years; Known duration: 0 years; Known duration: 1-5 years; Known duration: 6-10 years; Known duration: 11-15 years; Known duration: 16-20 years; Known duration: 21-25 years; Known duration: 26-30 years; Known duration: 31-35 years; Known duration: 36+ years; Sex: men; Sex: women; No atrial fibrillation; Atrial fibrillation: old or present; Retinopathy: no; Retinopathy: yes; Treated hypertension: no; Treated hypertension: yes; Pulse pressure <50 mmHg; Pulse pressure 50-110 mmHg; Pulse pressure 111+ mmHg; HbA1c <6%; HbA1c 6-<9%; HbA1c 9+ %; Normoalbuminuria; Microalbuminuria; Macroalbuminuria; Non HDL-c <3 mmol/l; Non HDL-c 3-<6 mmol/l; Non HDL-c 6-<9 mmol/l; Non HDL-c 9+ mmol/l
Mesh TermsTo be updated
Number of Validations3

External Validations

Yes
3
0.67
1st Author Year Sample Size AUC Calibration Relatedness
Leeuw 2014 453 0.62 Yes Related
Leeuw 2014 1174 0.67 Yes Distantly Related
Leeuw 2014 584 0.68 Yes Related