| Model ID | 06-002-01 |
| Model Name | Candesartan in Heart Failure: Assessment of Reduction in Mortality and morbidity (CHARM) - CV Death or HF Hospitalization |
| Pubmed ID | 16219658 |
| First Author | Pocock |
| Journal | European Heart Journal |
| Year | 2006 |
| Title | Predictors of mortality and morbidity in patients with chronic heart failure |
| Primary Index Condition | Chronic Heart Failure (CHF) |
| Secondary Index Condition | N/A |
| Outcome | MACE |
| Model Sample Size | 7599 |
| Cohort Sample Size | 7599 |
| Number of Events | 2460 |
| Follow-Up Duration | Long (>6 months) |
| AUROC | 0.75 |
| Calibration Reported | 1 |
| Covariates | Age (per 10 years over age 60); Diabetes: insulin-treated; Diabetes: other; Ejection fraction (per 5% decrease below 45); Prior HF hospitalization within 6 months; Prior HF hospitalization but not within 6 months; Cardiomegaly; Diagnosis of CHF over 2 years ago; NYHA class III; NYHA class IV; DBP (per 10 mmHg decrease); Bundle branch block; Heart rate (per 10 bpm); Candesartan (vs. placebo); Dependent edema; Pulmonary crackles; Rest dyspnea; Female; Atrial fibrillation; BMI (per 1 kg/m^2 decrease below 27.5); Mitral regurgitation; Previous myocardial infarction; Pulmonary edema; Current smoker |
| Mesh Terms | To be updated |
| Number of Validations | 1 |
