Risk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator

Field Value
Model ID12-032-01
Model NameGlucose at presentation, Race, Age, Sex, systolic blood Pressure at presentation, and Severity of stroke at presentation (NIHSS) (GRASPS)
Pubmed ID22811458
First AuthorMenon
JournalStroke
Year2012
TitleRisk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator
Primary Index ConditionStroke
Secondary Index ConditionIschemic
OutcomeStroke
Model Sample Size7169
Cohort Sample Size10242
Number of Events496
Follow-Up DurationShort (<3 months)
AUROC0.71
Calibration Reported1
CovariatesAge <=60; Age 61-70; Age 71-80; Age >80; NIHSS 0-5; NIHSS 6-10; NIHSS 11-15; NIHSS 16-20; NIHSS >20; Systolic blood pressure <120 mmHg; Systolic blood pressure 120-149 mmHg; Systolic blood pressure 150-179 mmHg; Systolic blood pressure >=180 mmHg; Blood glucose <100 mg/dl; Blood glucose 100-149 mg/dl; Blood glucose >=150 mg/dl; Ethnicity: Asian; Ethnicity: non-Asian; Gender: male; Gender: female
Mesh TermsTo be updated
Number of Validations5

External Validations

Yes
5
0.67
1st Author Year Sample Size AUC Calibration Relatedness
Sung 2013 548 0.62 Yes Related
Van Hooff 2014 169 0.66 No Distantly Related
Strbian 2014 3012 0.67 Yes Distantly Related
Li 2015 811 0.70 No Distantly Related
Watson-Fargie 2015 431 0.74 No Distantly Related