The International Heart Transplant Survival Algorithm (IHTSA): a new model to improve organ sharing and survival

Field Value
Model ID15-004-01
Model NameInternational Heart Transplant Survival Algorithm (IHTSA)
Pubmed ID25760647
First AuthorNilsson
JournalPLoS One
Year2015
TitleThe International Heart Transplant Survival Algorithm (IHTSA): a new model to improve organ sharing and survival
Primary Index ConditionHeart Transplant
Secondary Index ConditionN/A
OutcomeMortality
Model Sample Size41780
Cohort Sample Size50349
Number of Events22687
Follow-Up DurationLong (>6 months)
AUROC0.6
Calibration Reported1
CovariatesRecipient: diagnosis - non-ischemic cardiomyopathy; Recipient: diagnosis - ischemic cardiomyopathy; Recipient: diagnosis - congenital; Recipient: diagnosis - graft failure; Recipient: diagnosis - valve heart disease; Recipient: diagnosis - other; Recipient: age (years); Recipient: gender (female); Recipient: height (cm); Recipient: weight (kg); Recipient: insulin treated diabetes; Recipient: hypertension; Recipient: infection within two weeks; Recipient: antiarrhythmic drugs prior to transplant; Recipient: amiodarone prior to transplant; Recipient: recipient blood group; Recipient: previous blood transfusion; Recipient: previously transplanted; Recipient: previous cardiac surgery; Recipient: intensive care unit; Recipient: mechanical ventilation; Recipient: ECMO; Recipient: ventricular assist device; Recipient: transplant era ( -1995); Recipient: transplant era (1996-2000); Recipient: transplant era (2001-2005); Recipient: transplant era (2006- ); Recipient: SBP (mmHg); Recipient: PVR (wood units); Recipient: creatinine (umol/l); Recipient: serum bilirubin (umol/l); Recipient: PRA > 10%; Recipient: HLA-DR 2 mismatch; Donor: age (years); Donor: gender (female); Donor: height (cm); Donor: weight (kg); Donor: duration of ischemia (min); Donor: blood group; Donor: cause of death
Mesh TermsTo be updated
Number of Validations2

External Validations

Yes
2
0.6175
1st Author Year Sample Size AUC Calibration Relatedness
Nilsson 2015 1285 0.59 Yes N/A
Nilsson 2015 6276 0.645 No N/A