The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making
| Field | Value |
|---|---|
| Model ID | 00-012-01 |
| Model Name | Thrombolysis in Myocardial Infarction (TIMI) Risk Score for non-ST-segment elevation myocardial infarction/ unstable angina (NSTEMI/UA) - Composite Endpoint |
| Pubmed ID | 10938172 |
| First Author | Antman |
| Journal | Journal of the American Medical Association |
| Year | 2000 |
| Title | The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making |
| Primary Index Condition | Coronary Artery Disease (CAD) |
| Secondary Index Condition | Acute Coronary Syndrome (ACS) |
| Outcome | MACE |
| Model Sample Size | 1957 |
| Cohort Sample Size | 1957 |
| Number of Events | 327 |
| Follow-Up Duration | Short (<3 months) |
| AUROC | NR |
| Calibration Reported | 1 |
| Covariates | Age >=65 y; At least 3 risk factors for CAD (family history of CAD, HTN, hypercholesterolemia, DM, or smoking); Significant coronary stenosis (e.g., prior coronary stenosis >=50%); ST deviation; Severe anginal symptoms (e.g., >=2 anginal events in last 24 h); Use of aspirin in last 7 days; Elevated serum cardiac markers |
| Mesh Terms | To be updated |
| Number of Validations | 20 |
External Validations
| Yes | |
| 20 | |
| 0.67 |
| 1st Author | Year | Sample Size | AUC | Calibration | Relatedness |
|---|---|---|---|---|---|
| Chase | 2006 | 1354 | NR | No | Mismatch |
| Kim | 2011 | 1261 | NR | No | Distantly Related |
| Soiza | 2005 | 869 | NR | Yes | Distantly Related |
| Martinoni | 2012 | 3214 | NR | No | Mismatch |
| Conti | 2016 | 589 | 0.56 | No | Distantly Related |
| Antman | 2000 | 1607 | 0.59 | Yes | Distantly Related |
| Antman | 2000 | 1953 | 0.61 | Yes | Closely Related |
| Liu | 2014 | 564 | 0.621 | No | Distantly Related |
| Morrow | 2002 | 1915 | 0.64 | Yes | Distantly Related |
| Antman | 2000 | 1564 | 0.65 | Yes | Distantly Related |
| Huang | 2014 | 747 | 0.654 | No | Distantly Related |
| Sanchis | 2005 | 646 | 0.66 | No | Distantly Related |
| Bartholomew | 2004 | 237 | 0.68 | No | Related |
| Chen | 2016 | 833 | 0.689 | No | Distantly Related |
| Liu | 2014 | 648 | 0.71 | No | Distantly Related |
| Backus | 2013 | 2388 | 0.75 | No | Distantly Related |
| Lee | 2011 | 4743 | 0.757 | Yes | Distantly Related |
| Tong | 2005 | 957 | 0.77 | No | Distantly Related |
| Body | 2009 | 796 | 0.77 | No | Mismatch |
| Tong | 2014 | 678 | 0.862 | No | Distantly Related |